Neurosurgery Department, UF College of Medicine
Research: Clinical Trials
The development of more effective treatment requires that new and innovative therapies be evaluated in patients. The Preston A. Wells, Jr., Center for Brain Tumor Therapy at the University of Florida, provides brain tumor patients with opportunities to participate in clinical trials. The Preston Wells Center, which is co-directed by Dr. William A. Friedman and Dr. Erin M. Dunbar, focuses on basic, translational, and clinical research in the areas of primary and metastatic brain tumors.
Clinical trials are research studies designed to evaluate the safety and effectiveness of new drugs or treatment strategies. The information gained from clinical trials is essential for improving survival, improving quality of life, and leading to higher standards of care.
To learn more about our available clinical trials, please review the clinical trial listings below.
| Current Clinical Trials: | Contact: | |
|---|---|---|
| CENTRIC | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status | , 352-273-9000 |
| RTOG 0627 | Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma |
, 352-265-0316 |
| HGG-001 | Pilot Study to Determine Therapeutic Response of Oral Capecitabine (Xeloda) in Recurrent High Grade Gliomas (HGGs) by Establishing the Radiographic Response Rate Using Modified Macdonald Criteria |
,
352-273-9000 |
| RTOG 0424 | A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High-Risk Low-Grade Gliomas |
, 352-265-0316 |
| METS-001 | A Phase II Study of Temozolomide (TMZ) Following Stereotactic Radiosurgery (SRS) for Patients With Newly Diagnosed Brain Metastases |
,
352-273-9000 |
| ECOG-1F05 | Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma | ,
352-273-9000 |
| PCNSL-001 | Pilot Study to Determine Therapeutic Response of Pemetrexed (Alimta) in Recurrent or Progressive Central Nervous System Lymphoma (PCNSL) by Establishing the Radiographic Response Rate Using Modified Macdonald Criteria |
,
352-273-9000 |
| FCBTR | Establishment of a UF Brain Tumor Tissue Bank: Florida Center for Brain Tumor Research |
,
352-273-9000 |
| TCGA | The Cancer Genome Atlas |
, 352-273-9000 |
| QOL-001 | Do Self-rated Karnofsky Performance Status (KPS) Scores Correlate with Health-care-provider-rated KPS Scores? |
,
352-273-9000 |
| HEP-001 | The Effects of Adding a Home Exercise Program (HEP) to a Clinical Physical Therapy Program (CPTP) on the Cancer-Related Fatigue Reported by Patients Undergoing Concurrent Radiation and Chemotherapy for High-Grade Glioma (HGG) |
,
352-273-9000 |
| PICS | Penumbra Imaging Collaborative Study (PICS): A Multicenter Trial to Assess Outcome of Patients Revascularized by the Penumbra System |
, 352-273-9000 |
| SAMMPRIS | Stenting and Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis | , 352-273-9000 |
| CABANA | A Carotid Stenting Boston Scientific Surveillance Program |
, 352-273-9000 |
| SAPPHIRE | Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy |
,
352-273-9000 |
| PAC | Evaluation of Presidio and Cerecyte Coils in Large and Giant Aneurysms |
,
352-273-9000 |
| FIA II | Familial Intracranial Aneurysm Study II |
,
352-273-9000 |
| PRET | Patients Prone to Recurrence After Endovascular Treatment: A Randomized Trial Comparing Platinum and Hydrogel-Coated Coils |
,
352-273-9000 |
| STASH | Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH)-A Multicentre Randomised Controlled Clinical Phase III Study | ,
352-273-9000 |
| 479-2009 | Patient Comfort Study With Vascular Closure: Mynx vs. Angio-Seal Evolution | , 352-273-9000 |
For up-to-date information of ACTIVE and PENDING trials, please contact *, in the research office of the Department of Neurosurgery at the University of Florida, at (352) 273-7981 or (352) 273-9000 or (800) 633-2122 ext 39000.
Related Links
ClinicalTrials.gov is a registry of federally and privately supported clinical trials conducted in the United States and around the world.
The Florida Cancer Clinical Trial Matching Service offers patients, caregivers and health care professionals up-to-date information about cancer clinical trials in Florida and throughout the United States.
The National Cancer Institute's registry of available clinical trials, clinical trial results, and educational materials.
The Musella Foundation, Clinical Trials and Noteworthy Treatments for Brain Tumors